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Symbol
Name
ID
Sav1
salvador family WW domain containing 1
MGI:1927144
Phenotype annotations related to liver/biliary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
liver/biliary system phenotype
increased hepatocyte proliferation
bile duct hyperplasia
enlarged liver
increased liver weight
abnormal liver morphology
abnormal hepatocyte morphology
abnormal portal lobule morphology
abnormal oval cell morphology
increased liver tumor incidence
increased hepatocellular carcinoma incidence
increased hepatoma incidence
increased liver adenoma incidence
abnormal oval cell physiology
Availability Mouse Genotype
Sav1tm1Dlim/Sav1tm1Dlim
Sav1tm1.1Gpp/Sav1+
Sav1tm1Dlim/Sav1+
Sav1tm1.1Rjo/Sav1tm1.1Rjo
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)
Sav1tm1.1Rjo/Sav1tm1.1Rjo
Tg(MMTV-cre)4Mam/0  (conditional)
Sav1tm1.1Rjo/Sav1tm1.1Rjo
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
Sav1tm2.1Dlim/Sav1tm2.1Dlim
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory