Symbol Name ID |
Sav1
salvador family WW domain containing 1 MGI:1927144 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | liver/biliary system phenotype |
increased hepatocyte proliferation |
bile duct hyperplasia |
enlarged liver |
increased liver weight |
abnormal liver morphology |
abnormal hepatocyte morphology |
abnormal portal lobule morphology |
abnormal oval cell morphology |
increased liver tumor incidence |
increased hepatocellular carcinoma incidence |
increased hepatoma incidence |
increased liver adenoma incidence |
abnormal oval cell physiology |
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Availability | Mouse Genotype | ||||||||||||||
Sav1tm1Dlim/Sav1tm1Dlim | |||||||||||||||
Sav1tm1.1Gpp/Sav1+ | |||||||||||||||
Sav1tm1Dlim/Sav1+ | |||||||||||||||
Sav1tm1.1Rjo/Sav1tm1.1Rjo Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Sav1tm1.1Rjo/Sav1tm1.1Rjo Tg(MMTV-cre)4Mam/0 (conditional) |
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Sav1tm1.1Rjo/Sav1tm1.1Rjo Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Sav1tm2.1Dlim/Sav1tm2.1Dlim Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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